منابع مشابه
Transplacental arsenic carcinogenesis in mice.
Our work has focused on the carcinogenic effects of in utero arsenic exposure in mice. Our data show that a short period of maternal exposure to inorganic arsenic in the drinking water is an effective, multi-tissue carcinogen in the adult offspring. These studies have been reproduced in three temporally separate studies using two different mouse strains. In these studies pregnant mice were trea...
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Although B-carotene has been considered to be a key cancer preventive agent in green and yellow vegetables, other types of carotenoids, such as a-carotene, may also contribute to anticarcinogenic action, since these carotenoids usually coexist with/~-carotene and are detectable in human blood and tissues. In this study, we compared the inhibitory effect of natural a-carotene, obtained from palm...
متن کاملFactors modifying experimental epidermal carcinogenesis in mice.
brought to visible tumors. Mottram (10) observed tumor production in mouse skin after exposing it to a single treatment with a carcinogenic hydrocarbon, followed by re peated applications of croton oil. Later, Berenblum and Shubik (3) adapted this method to a quantitative approach to the study of chemical carcinogenesis. According to this method, the actual number of tumors produced were said t...
متن کاملCD73-deficient mice are resistant to carcinogenesis.
CD73 is a cell surface 5'-nucleotidase that converts AMP to adenosine, an immune suppressive molecule. CD73 may promote immune escape in cancer by contributing to the degradation of extracellular ATP released by dying cancer cells in hypoxic tumors or following chemotherapy. However, whether CD73 exerts a critical oncogenic function during tumorigenesis is unknown. In this study, we used geneti...
متن کاملCarcinogenesis by urethan via mother's milk and its enhancement of transplacental carcinogenesis in mice.
Pulmonary tumors were induced in mice that were suckled by mothers that received urethan during lactation. More induced tumors appeared in sucklings when urethan was injected into lactating mothers soon after delivery. When pregnant mice were treated with urethan during gestation and lactation their offspring had a significantly increased incidence of pulmonary tumors, and the number of tumors ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1978
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1978.140